N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis

نویسندگان

  • Rob De Vreese
  • Matthias D’hooghe
چکیده

The interplay between metals and N-heterocyclic carbenes (NHCs) has provided a window of opportunities for the development of novel catalytic strategies within the past few years. The recent successful combination of Brønsted acids with NHCs has added a new dimension to the field of cooperative catalysis, enabling the stereoselective synthesis of functionalized pyrrolidin-2-ones as valuable scaffolds in heterocyclic chemistry. This Commentary will briefly highlight the concept of N-heterocyclic carbene/Brønsted acid cooperative catalysis as a new and powerful methodology in organic chemistry.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2012